Eribulin Synthesis Essays

Found 3785 essays.

Organic Synthesis of Polymers | Essay

The significance of these reagents is mostly felt in the new method of combinatorial synthesis, where high output stage phase synthesis is deliberated with polymer supported reagents.Polymer-supported synthesis (PSS) process involves the momentary coupling of synthesis substrates to a polymer carrier and thus curtails product purification and isolation to simple filtration and washing exercises.The use of suitable additions of polymer-supported reagents, catalysts and/or scavengers is a powerful method, both for the synthesis of single organic compounds and for parallel synthesis.introduced the synthesis of chloro and bromopolymaleimide and used as halogenating agents.Various researches indicate that poly ( bromomaleimide) has not bee...

1854 words (4.6 pages)
Heterocycles: Types and Biosynthesis

They have focused most of their attention on the synthesis of nitrogen containing heterocycles by the condensation of ketoalkynes with ammonia.Scheme 14: One pot synthesis of isoindolinones .As indoles are structural components of a large number of biologically active natural compounds, their synthesis and functionalization has been heavily researched, and is a crucial step in the preparation of many pharmaceutical compounds.Another example of a tandem reaction for heterocyclic synthesis is the intermolecular 1,3-dipolar cycloaddition of nitrones for the formation of cyclic isooxazolidines ( .Two of the most common are: Fischer-indole synthesis and a Hantzsch synthesis to obtain the pyridines.

2943 words (7.4 pages)
Importance of Natural Product Synthesis

It also serves to improve chemical synthesis by attempting to push its frontiers into higher molecular complexity, diversity, and efficiency.Today the art of organic synthesis has improved to astoundingly high levels of sophistication.Some modern classical examples of total synthesis include the synthesis of prostaglandin PG and Ginkgolide by E. J Corey, Ingenol by Wood, Brevetoxin by Nicolaou, Vancomycin by Evans, Taxol by Holton , Nicolaou , Wender and Danishefsky groups independently.This event ushered in the modern era of total synthesis and Woodward who received the 1965 Nobel Prize for Chemistry for several brilliant examples of total synthesis such as his 1954 synthesis of strychnine, cholesterol is regarded as the “father” o...

1330 words (3.3 pages)
Explanatory Synthesis Essay

The two types of synthesis discussed in this text are the explanatory synthesis (discussed in Chapter 4) and the argument synthesis (discussed in Chapter 5).The argument synthesis also uses two or more sources; however, its primary purpose is to convey an opinion or interpretation of these sources, not merely a presentation of them.The explanatory synthesis uses two or more sources to convey information about a given topic; it does not provide for the writer’s opinion on the topic.In the explanatory synthesis, writers divide a subject into its component parts and present them to the reader in a clear and orderly fashion.In developing a thesis for your explanatory synthesis, base your thesis on an idea that is .

1638 words (4.1 pages)
Marine Genomes in Nanoparticles (NPs) Synthesis

The marine seaweed are excellent source for the synthesis of the zinc, the seaweeds extracts such as , red and brown are used as the reducing and stabilizing agent for the NPs synthesis.Followed by few researchers reported the NPs synthesis by using Marine fungus.Several researchers are reported the efficiency of the marine fungus on the NPs synthesis with high pharmaceutical applications.Microbial capping agents are added as the stabilizer in to the reaction of the NPs synthesis to ensure the prevention of the aggregation and uniform morphology of the NPs and prevent the extraordinary issue of NPs research in chemical syntheses.Interestingly the Vala (2014) reported the efficiency of the on synthesis of gold NPs.

2476 words (6.2 pages)
Synthesis of New Coordination Polymers or MOFs

Synthesis of porous MOF by mechanochemical reaction was reported first in 2006 [89].However, mechanochemical synthesis is limited to specific MOF types only and large amount of product is difficult to obtain.The synthesis parameters such as solvent, electrolyte, voltage-current density, and temperature on the synthesis yield and textural properties of the MOFs obtained, was investigated and the produced MOF structures were characterized by X-ray diffraction, gas adsorption, atomic force microscopy, diffuse reflectance infrared Fourier transform spectroscopy, and scanning electron microscopy.Recently, a mechanochemical approach was also applied for ZIF synthesis using combinations of ZnO and imidazole (HIm), 2-methylimidazole (HMeIm), and...

2182 words (5.5 pages)
How to Write a Synthesis Essay

It will frequently be helpful for your readers if you provide at least partial summaries of sources in your synthesis essays.The explanatory synthesis does not go much beyond what is obvious from a careful reading of the sources.Since the very essence of synthesis is the combining of information and ideas, you must have some basis on which to combine them.You will not be writing explanatory synthesis essays in this course.Two Types of Syntheses Essays - explanatory synthesis and argument synthesis .

786 words (2.0 pages)
Synthesis and Anticancer Activities of 5-halogeno Pyrimidine

Kidwai and Rastogi reported an eco friendly approach for the synthesis of 2 substituted-4-6-diarylpyrimidines using inorganic solid supports for its catalytic roleas well as energy transfer medium is described.The methodology eliminates the usage of solvents during reaction.Microwave assisted basic alumina catalysed reaction is the best as a catalysis as well as reaction time and yield.Microwave- assisted synthesis has been applied in many formats ranging from traditional solution phase to solid phase and solvent free reactions.Solid state microwaves assisted organic synthesis have an impact on drug discovery.have made the solvent and catalyst-free synthesis of dihydropyrimidione in one pot conditions under focused microwave irradiation ...

1443 words (3.6 pages)
Synthesis of API’s and API’s based Derivative

In this project we will focus on the establishment of synthetic organic laboratory, the synthesis of the two API’s (Secnidazole & Atenolol).Proposed Two-Step Synthesis route for Atenolol .And Ph.D. scholars in the field of Organic Synthesis.The synthesis of API could decrease the import bill of such active ingredient in Pakistan and also opens the opportunity of job.The purpose of this project is to setup a laboratory which can design (Organic Synthesis) and synthesize (Organic Synthesis) the APIs for the local Pharmaceutical industry along with the establishment of the required facilities.

900 words (2.3 pages)
Relationship Between Neoliberalism and Neorealism

Deeply influenced and threatened by the persuasiveness of such ideas, and so by the notion that their own ideological differences might become superfluous; scholars of both schools created the ‘neo-neo synthesis’ as a self-defence mechanism.Ruggie, J. G. (1986) ‘Continuity and Transformation in the World Polity: Toward a Neorealist Synthesis’ in Keohane, R. O.If this constructivist position is accurate, Ruggie argued, then the neo-neo synthesis cannot also be accurate.A further attack upon the solidity of the neo-neo synthesis has been launched by the deconstructivism school founded by Richard Ashley (1988) and David Campbell (1998) ─ the criticisms of both centring upon failure of the neo-neo synthesis to properly explain the anarchic...

1725 words (4.3 pages)
Writing a Synthesis

In order to write a successful synthesis essay, you must gather research on your chosen topic, discover meaningful connections throughout your research, and develop a unique and interesting argument or perspective.A synthesis is not a summary.In this essay, the author found various sources on the same topic (the purposes of U.S. forces in Vietnam) and used certain parts of those sources to support the thesis statement.However, the purpose of a synthesis essay is to use only the most important parts of your research, the information that will best support your claim.The guiding ideas of the paper—the thesis statement at the end of the first paragraph and the corresponding topic sentences—are highlighted in gray.

475 words (1.2 pages)
Intracellular Biosynthesis of Cadmium Sulfide Nanoparticles

The optimum condition for synthesis of nanoparticles is temperature of 30ºC and pH of 9. .Development of protocols for the synthesis of such semiconductors (the so-called quantum dots) is growing.The development of techniques for the controlled synthesis of nanoparticles of well defined size, shape and composition, to be used in the biomedical field and areas such as optics and electronics, has become a big challenge.Development of reliable and eco-friendly processes for synthesis of metallic nanoparticles is an important step in the field of application of nanotechnology.To obtain the optimum concentration of CdCl2 and Na2S that yields the maximum synthesis of nanoparticles and particle-size distribution, CdCl2 and Na2S, at concentratio...

2068 words (5.2 pages)
Chemical Synthesis of a Gene: Phosphodiester Approach

The solid support is contained in columns whose dimensions depend on the scale of synthesis.For synthesis of a gene, the oligonucleotides (about 30-60 nt long) are synthesized chemically so that each oligonucleotide has a 6-9 nt overlap with its neighboring oligonucleotide.The synthesis is carried out in several steps described below: ..(ii) Synthesis of the entire sequence of the DNA of interest: five to ten PCR products from the first step are combined and used as the template for a second PCR reaction using high-fidelity DNA polymerase pyrobest, with the two outermost oligonucleotides as primers.Besides, other methods in use for gene synthesis are successive extension PCR, simplified gene synthesis (PCR based), synthons and ligation b...

1979 words (4.9 pages)
Explanation of the Multistep Synthesis of Benzilic Acid Essay

Benzilic Acid Synthesis .The synthesis of several complex organic compounds follows a multistep synthesis.During the conversion of benzoin to benzil, some benzoin may remain unoxidized.Benzil Synthesis .The multistep synthesis of benzilic acid begins with a conversion benzaldehyde to benzoin through a condensation reaction.

409 words (1.0 pages)
Lipase Catalysed Synthesis of Bio-based Reactive Polyester

During the synthesis all reaction were remained inhomogenous and gave only low molecular weight product with Mn values between 150 and 390 as determined by GPC analysis.Title of the paper is Green polymer chemistry: lipase catalysed synthesis of bio-based reactive polyester employing itaconic anhydride as renewable monomer”.The authors used some references to state the method for poly lactide synthesis using two method ring opening polymerization of lactide and direct polycondensation of lactic.From the extension of an all these studies the current paper include lipase catalysed synthesis reactive polyester employing itaconic anhydride (IAn), succinic anhydride (SAn) or glutaric anhydride as starting monomer with for diol.The strategy o...

2045 words (5.1 pages)
One-pot Synthesis of Porous Coordination Polymers

Therefore, controllable synthesis of well-defined NMOF crystals with specific exposed crystal facets in the nano/micrometer range is highly desirable.To date, several synthetic strategies have been employed by research groups for the synthesis of NMOFs such as room-temperature precipitation, hydro/solvothermal techniques, microwave-assisted synthesis, sonochemical synthesis and electrochemical synthesis method.The gas adsorption properties of MOF-14 with different shapes were also studied and it reveal that properties of MOF-14 display a strong dependence on the facets exposed on the surface.To date, many research efforts have been focused on the design, synthesis and applications of bulk MOFs materials; however, nanosized MOFs (N...

1001 words (2.5 pages)
Protein Synthesis in DNA Processes

There are four stages in the formation of the proteins, these are: synthesis of amino acids; transcription; amino acid activation and translation.The first stage, the synthesis of amino acids, is concerned with the formation of amino acids.Protein synthesis is the process that is concerned with transfer of the information from the triplet code on the DNA to ensure the formation of the proteins.The fourth and final stage of protein synthesis occurs in the cytoplasm at the ribosomes, and is called translation.The messenger RNA passes through the nucleus and enters the cytoplasm where is connects with the ribosomes and acts as a template for protein synthesis.

1676 words (4.2 pages)
Synthesis of Carbon Nanotubes at Low Temperatures Using Single Heating Source of Catalyst and Reactor in the Floating Catalyst Chemical Vapor Depositi

Materials Chemistry and Physics, 72, 223-227.Large-scale synthesis of carbon nanotubes by plasma rotating arc discharge technique Lee, Y., Kim, N., Park, J., Han, J., Choi, Y., Ryu, H., Lee, H. (2003).Kinetic study of carbon nanotube synthesis over Mo/Co/MgO catalysts.Low-temperature growth and field emission of aligned carbon nanotubes by chemical vapor deposition.Many methods for the synthesis of CNTs have been used and developed (Ajayan, 1992; Ishigami et al., 2000; Lee et al., 2002).

398 words (1.0 pages)
Style Guide and Essay

You should keep in mind that this is a more formal essay than the journalistic style of the place profile, and thus should be more tightly organized with an introduction, topic sentence to introduce paragraphs, at least three supporting evidence paragraphs, and a conclusion.You should use these two sources to support your .Your essay should concentrate on a single theme (or topic) in Abbey’s work and should integrate at least two outside sources (this is the synthesis part), one of which can be the critical essay I posted in Week 7’s Lesson.Synthesis Essay Assignment: Construct a three page thematic analysis of Edward Abbey’s Desert Solitaire.A successful essay of this type should include a thesis statement (your opinion of Abbey’s use...

3493 words (8.7 pages)
Mechanisms of Rapamycin Production Discrepancy

In fact, both isoleucine and valine are the precursor of methylmalonyl-CoA [22, 24]which is a key node of the carbon flux switches from the primary branch into the secondary metabolic branch [29, 33] such asrapamycin[19].Therefore, more isoleucine and valine in mutant strain might be used to supply methylmalonyl–CoA for rapamycin synthesis.As described above, it was concluded that amino acids metabolism including lysine and arginine, valine, glutamate, isoleucine and ornithine, were key for rapamycin synthesis.In sum, more amino acids were used to supply precursors of rapamycin synthesis in the mutant strain, compared to that in the wild-type.In addition, the result indicated the shortage of valine, glutamate, isoleucine, and ornithine ...

1640 words (4.1 pages)
Effects of Light and Cell Cycle on Expression Level of EChR1

In addition, the result indicated the shortage of valine, glutamate, isoleucine, and ornithine in the synthesis of rapamycin (Fig.The depletion of intracellular tryptophan or the high level of tryptamine might indicate the activation of shikimatemetabolic pathway, and more DHCHC available for rapamycin synthesis.In fact, both isoleucine and valine are the precursor of methylmalonyl-CoA [22, 24]which is a key node of the carbon flux switches from the primary branch into the secondary metabolic branch [29, 33] such asrapamycin[19].Therefore, more isoleucine and valine in mutant strain might be used to supply methylmalonyl–CoA for rapamycin synthesis.Thus, it might be speculated that urea cycle might be potential key metabolic module to pr...

1619 words (4.0 pages)
Erythryloxum coca Essay

However, a second synthesis by Spi??tter worked on a tortuous synthesis (of about 20 steps) of tropinone between 1900 and 1903, but in 1917 Robinson reported his ‘one-pot’ synthesis and also provided what was probably the first example of a formal retrosynthetic analysis.The laboratory synthesis of an alkaloid can be a challenging problem.The structure of nicotine was finally confirmed by synthesis.A simple synthesis can provide an alternative supply of such a drug.

1927 words (4.8 pages)
Synthesis of Carbon Nanotubes at Low Temperatures Using Single Heating Source of Catalyst and Reactor in the Floating Catalyst Chemical Vapor Depositi

Shyu, Y., Hong, F. (2001).Low-temperature growth and field emission of aligned carbon nanotubes by chemical vapor deposition.The interesting morphology of CNTs produced at relatively low temperature promotes real opportunity to minimize the synthesis temperature of CNTs in the future works.Materials Chemistry and Physics, 72, 223-227.Keywords Carbon nanotubes; Floating catalyst; Single heating source; low synthesis temperature Introduction: Since their first discovery in 1991 (Iijima, 1991), carbon nanotubes have attracted much attention due to their nanoscale dimensions and promising shape as well as their potential properties.

391 words (1.0 pages)
Diketo Analogues and Their Significance

Medicinal chemistry is the branch of science, which has remarkable value for synthesis of novel drugs with intense therapeutic activity.Mosharef Hossain reported synthesis of thieno[3,2-e] imidazo[1,2-c] pyrimidin-2(3H)ones (39) which was evaluated for antimicrobial activity against and compare to reference drugs Ampicillin with Nystatin.Shetty Nitin kumar reported synthesis of 8,9,10,11-tetrahydro[1]benzothieno[3,2-e] [1,2,4]triazolo [1,5- c]pyrimidine -8-ones (40-42) and evaluated for antibacterial activity against comparable to ampicilin.Ahmed M. M. reported synthesis of 4-(substituted)-7-cyano- 6-phenyl aminothieno [3,2-d] pyrimidins (33-34) and evaluated as good antimicrobial agents by using B.subtilis and compared with refer...

769 words (1.9 pages)
Carbon Nonmaterial From Non-renewable Oil Resource Synthesis

Catalytic CVD Synthesis of Carbon Nanotubes: Towards High Yield and Low Temperature Growth.Synthesis process has been carried out at temperature of 500 and 570 °C for precursor and CNTs synthesis, respectively, a ferrocene catalyst concentration was 17.99 wt%.Synthesis and Characterization of Multi-Walled Carbon Nanotubes from Biodiesel Oil: Green Nanotechnology Route.The third objective of the project is to optimize the CNTs synthesis parameters such as; temperature, flow rate, precursor type used, and catalysis type.This makes the optimization process for synthesis of CNTs from non renewable precursors highly demanding.

1713 words (4.3 pages)
The prokaryote cell Essay

and contains enzymes for lipid biosynthesis, especially the synthesis of phospholipids and steroids.Membranes also contain enzymes involved in many metabolic processes such as cell wall synthesis, septum formation, membrane synthesis, DNA replication, CO2 fixation and ammonia oxidation .The cell membrane has a number of functions related to respiration, and ATP synthesis.The nucleus  in eukaryotic cells is separated from the cytoplasm by a nuclear envelope (nuclear membrane).ER with ribosomes attached is called rough endoplasmic reticulum and is involved in protein synthesis, production of new membrane, modification of newly formed proteins, and transport of these proteins and membrane to other locations within the cell.

593 words (1.5 pages)
Long-term empowerment Essay

In addition, β-adrenergic receptor agonists such as norepinephrine, may alter the late phase of PLT dependent on protein synthesis.the late phase of PLT is also associated with presynaptic synaptotagmin synthesis and an increased number of synaptic vesicles, suggesting that L-LTP induces protein synthesis not only in postsynaptic cells, but also in post-synaptic cells.In contrast, the overall protein synthesis that occurs in the cell body requires that proteins be shipped to all regions of the cell, including synapses that have not received PLT-inducing stimuli.More precisely, if indeed protein synthesis is the basis of L-LTP, only dendritic spines receiving PLT-inducing stimuli will be subjected to the latter; the potentiation will not ...

4109 words (10.3 pages)
Synthesis Of Multicomponent Reactions Using Nanomagnetic Catalyst Under Solvent Free Condition

It was observed that the yields of the product remained comparable in these experiments (Figure 3), established the recyclability, and the reusability of the catalyst without any significant loss of activity.To examine the reusability, the catalyst was recovered by an external magnet from the reaction mixture after it was washed with methanol or acetone and dried in the air....ves a cleaner reaction than acetophenone.The possible mechanism for the nano-γ-Fe2O3-SO3H catalyzed synthesis of substituted 3, 4-dihydropyrimidin-2-(1H)-ones has been proposed in figure 2.Currently the ideal synthesis in organic chemistry means that a product is made in one step in the process of adapting to green chemistry [4].

419 words (1.0 pages)
Bark Extract Mediated Green Silver Nanoparticles Synthesis

Various plants parts have been used for the synthesis of silver nanoparticles but rarely the barks have been used.The extracts contains different enzymes/proteins, amino acids, polysaccharides, vitamins, poly phenols, etc., which act as both reducing and capping agents during the nanoparticle synthesis [8].1 shows the time taken for the total synthesis of the nanoparticles when the reaction mixture was incubated at 80 ºC.Although the exact mechanism for the reduction of silver nanoparticles is not know Ajitha proposed that the flavonoids present in leaf extract may act as powerful reducing agent and the carboxylate group present in the proteins may act as surfactant to attach on the surface of the nanoparticles resulting in their stabi...

2681 words (6.7 pages)
Chemistry: New Era for Organic Semiconducting Polymers

Synthesis of Regioregular polyalkylthiophenes (PATs) .Regioregular synthesis results in well defined 2,5- coupled polyhtiphenes, which eliminates ambiguous structure-property relationship and allows for efficient performances in optoelectronic applications.7, 31, 32 Due to the ability to form distinct regioisomers, polythiphenes became the most studied conjugated semi conducting polymers for organoelectronic applications.6, 33, 34 The simplest way to describe the 3-alkythiophene couplings is by denominating the sterically crowded 2-position as the ‘‘head’’ and 5-position as the ‘‘tail’’.1 .reported the synthesis of PATs from 2,5-diiodo-3-alkylthiophenes using Ni(0) as the catalyst, and claimed that diiodothiophenes are more active monome...

2526 words (6.3 pages)

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