Chronic polyradiculoneuritis Essay


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Chronic polyradiculoneuritis, or chronic inflammatory demyelinating polyradiculoneuritis, (CIDP) is an autoimmune disease affecting the peripheral nervous system. This disease is classified under the more general name of peripheral neuropathy. IPDC is a close relative of Guillain-Barré syndrome (or Acute Idiopathic Polyradiculoneuropathy) and is considered its chronic counterpart. Its symptoms are also similar to progressive inflammatory neuropathy, a highly asymmetric variant of CIDP, known as Lewis-Sumner syndrome. The prevalence, estimated between 1/200,000 (children) and 1-7 / 100,000 (adults), is undoubtedly underestimated.


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The diagnosis is based on a set of criteria from: . The treatment depends on the severity of the CIDP, the age, the general condition of the patient and the contraindications to the following validated treatments: . Patients with purely motor CIDP should be given intravenous immunoglobulin infusions rather than steroids. In more moderate forms, clinical observation via an electroneuromyogram (ENMG), or even corticosteroid therapy are indicated. The combination of steroids and immunoglobulin infusion are possible.


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The reason for relapses and remissions varies considerably from patient to patient. A period of relapse can be very disturbing, but most patients make a significant recovery. The prognosis is generally good. If it is early, the initiation of treatment to prevent loss of nerve axons is recommended. However, many people end up with residual numbness, weakness, tremors, fatigue and other symptoms that can lead to a reduced quality of life.


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